Testosterone ELISA

Catalog No. EIA1559
Tests 96 wells
Range 0.083 – 16 ng/mL
Sensitivity 0.083 ng/mL
Sample Volume 25 uL
Incubation Time(s) 60 / 15 min
Storage Conditions 2° C – 8° C

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SKU: DRG EIA1559 Category: Tag:

Description

DRG® Testosterone ELISA (EIA-1559)

Product: ELISA Kits

Brand: DRG

Intended Use

The DRG Testosterone ELISA is an enzyme immunoassay for the quantitative in vitro diagnostic measurement of Testosterone in serum and plasma.

Summary and Explanation

Testosterone (17β-hydroxy-4-androstene-3-one) is a C19 steroid with an unsaturated bond between C-4 and C-5, a ketone group in C-3 and a hydroxyl group in the β position at C-17. This steroid hormone has a molecular weight of 288.47. Testosterone is the most important androgen secreted into the blood. In males, testosterone is secreted primarily by the Leydig cells of the testes; in females ca. 50% of circulating testosterone is derived from peripheral conversion of androstenedione, ca. 25% from the ovary and ca. 25% from the adrenal glands. Testosterone is responsible for the development of secondary male sex characteristics and its measurements are helpful in evaluating the hypogonadal states. In women, high levels of testosterone are generally found in hirsutism and virilization, polycystic ovaries, ovarian tumors, adrenal tumors and adrenal hyperplasia. In men, high levels of testosterone are associated to the hypothalamic pituitary unit diseases, testicular tumors, congenital adrenal hyperplasia and prostate cancer. Low levels of testosterone can be found in patients with the following diseases: Hypopituitarism, Klinefelter’s syndrome, Testicular feminization, Orchidectomy and Cryptorchidism, enzymatic defects and some autoimmune diseases.

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